Keywords
redox
UV-Vis spectrophotometry
emerging contaminant
endocrine disruptor
chemical analysis
How to Cite
Abstract
Bisphenol A is an emerging contaminant and endocrine disruptor; therefore, the continuous development of analytical methods for its determination is pertinent. In this work, a new analytical method based on UV-Vis spectrophotometry is proposed for the determination of bisphenol A in water and thermal paper is proposed, based on a reaction with Fe3+ and Fe(CN)63-, giving Turnbull blue as a product; these reactions have already been documented. Using the proposed method, indirect quantification of this compound in the range of 100 to 1.500 μg L-1 was possible. The accuracy was estimated to be 94 ± 15, calculated as the average ± standard deviation in the recovery of 13 synthetic samples. The limits of detection and determination were 28 and 94 μg L-1, respectively. Finally, the method was applied to the analysis of water samples contained in polycarbonate containers, before and after exposure to microwave radiation, the BPA concentration being in all cases below the detection limit. Receipts issued in thermal paper between 2018 and 2019 in Saltillo, Coahuila, were also analyzed, finding concentrations between 0.8 and 2.7 %, comparable to those reported by other authors for this type of samples.
References
Atapattu, S. N. & Rosenfeld, J. M. (2022). Analytical derivatizations in environmental analysis. Journal of Chromatography A, 1678, 463348. https://doi.org/10.1016/j.chroma.2022.463348
Babu, S., Uppu, S. N., Martin, B., Agu, O. A. & Uppu, R. M. (2015). Unusually high levels of bisphenol A (BPA) in thermal paper cash register receipts (CRs): development and application of a robust LC-UV method to quantify BPA in CRs. Toxicology Mechanisms and Methods, 25(5), 410–416. https://doi.org/10.3109/15376516.2015.1045661
Basavaiah, K. & Prameela, H.C. (2003). Spectrophotometric determination of salbutamol sulphate and acyclovir using iron (III) and ferricyanide. ScienceAsia, 29, 141 – 146.
Burriel, F., Lucena, F., Arribas, S. & Hernández, J. (1994). Química analítica cualitativa, 15ª edición. Paraninfo.
Casado-Carmona, F. A., Lasarte-Aragonés, G., Lucena, R. & Cárdenas, S. (2023). Green sample preparation techniques in environmental analysis. In Gionfriddo, E. (Ed.), Green Approaches for Chemical Analysis (pp. 241-276). Elsevier.
Cimmino, I., Fiory, F., Perruolo, G., Miele, C., Beguinot, F., Formisano, P. & Oriente, F. (2020). International Journal of Molecular Sciences, 21(16), 5761. https://doi.org/10.3390/ijms21165761
Comisión Europea. (2016). Reglamento (UE) 2016/2235 de la Comisión de 12 de diciembre de 2016 que modifica, por lo que respecta al bisfenol A, el anexo XVII del Reglamento (CE) n.o 1907/2006 del Parlamento Europeo y del Consejo, relativo al registro, la evaluación, la autorización y la restricción de las sustancias y mezclas químicas (REACH). Diario Oficial de la Unión Europea, L 337/3, 13.12.2016. https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32016R2235
Comisión Europea. (2018). Reglamento (UE) 2018/213 de la Comisión de 12 de febrero de 2018 sobre el uso de bisfenol A en los barnices y revestimientos destinados a entrar en contacto con los alimentos y por el que se modifica el Reglamento (UE) n.o 10/2011 por lo que respecta al uso de dicha sustancia en materiales plásticos en contacto con los alimentos. Diario Oficial de la Unión Europea, L41/6, 14.2.2018. https://eur-lex.europa.eu/legal-content/ES/TXT/?toc=OJ%3AL%3A2018%3A041%3ATOC&uri=uriserv%3AOJ.L_.2018.041.01.0006.01.SPA
Corrales, J., Kristofco, L. A., Steele, W. B., Yates, B. S., Breed, C. S., Williams, E. S. & Brooks, B. W. (2015). Global assessment of bisphenol A in the environment: review and analysis of its occurrence and bioaccumulation. Dose-Response, 13(3), 1-29. https://doi.org/10.1177/1559325815598308
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids [CEP], Lambré, C., Barat Baviera, J. M., Bolognesi, C., Chesson, A., Cocconcelli, P.S., Crebelli, R., Gott, D.M., Grob, K., Lampi, E., Mengelers, M., Mortensen, A., Rivière, G., Silano, V., Steffensen, I.L., Tlustos, C., Vernis, L., Zorn, H., Batke, M., Bignami, M. … & van Loveren, H. (2023). Re-evaluation of the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs. EFSA Journal, 21(4), e06857. https://doi.org/10.2903/j.efsa.2023.6857
Frankowski, R., Zgoła-Grześkowiak, A., Grześkowiak, T. & Sójka, K. (2020). The presence of bisphenol A in the thermal paper in the face of changing European regulations – A comparative global research. Environmental Pollution, 265A, 114879. https://doi.org/10.1016/j.envpol.2020.114879
Geens, T., Goeyens, L., Kannan, K., Neels, H. & Covaci, A. (2012). Levels of bisphenol-A in thermal paper receipts from Belgium and estimation of human exposure. Science of the Total Environment, 435–436, 30–33. https://doi.org/10.1016/j.scitotenv.2012.07.001
Grand View Research. (2024). Thermal Paper Market Size, Share & Trends Analysis Report By Application (POS, Tags & Label, Lottery & Gaming), By Region (Asia Pacific, North America, Middle East & Africa, Europe), And Segment Forecasts, 2024 – 2030. Report ID 978-1-68038-690-5. https://www.grandviewresearch.com/industry-analysis/thermal-paper-market
Jadoon, S., Waseem, A., Yaqoob, M. & Adbul, N. (2010). Flow injection spectrophotometric determination of vitamin E in pharmaceuticals, milk powder and blood serum using potassium ferricyanide-Fe (III) detection system. Chinese Chemical Letters, 21, 712 – 715. https://doi.org/10.1016/j.cclet.2009.11.013
Jurek, A. & Leitner, E. (2018). Analytical determination of bisphenol A (BPA) and bisphenol analogues in paper products by LC-MS/MS. Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure, & Risk Assessment, 35(11), 2256-2269. https://doi.org/10.1080/19440049.2018.1524157
La Merrill, M. A., Vandenberg, L. N., Smith, M. T., Goodson, W., Browne, P., Patisaul, H. B., Guyton, K. Z., Kortenkamp, A., Cogliano, V. J., Woodruff, T. J., Rieswijk, L., Sone, H., Korach, K. S., Gore, A. C., Zeise L. & Zoeller, R. T. (2020). Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification. Nature Reviews Endocrinology, 16, 45–57. https://doi.org/10.1038/s41574-019-0273-8
Liao, C. & Kannan, K. (2011). Widespread occurrence of bisphenol A in paper and paper products: implications for human exposure. Environmental Science & Technology, 45(21), 9372–9379. https://doi.org/10.1021/es202507f
Ma, Y., Liu, H., Wu, J., Yuan, L., Wang Y., Du, X., Wang, R., Marwa, P. W., Petlulu, P., Chen, X. & Zhang, H. (2019). The adverse health effects of bisphenol A and related toxicity mechanisms. Environmental Research, 176, 108575. https://doi.org/10.1016/j.envres.2019.108575
National Center for Biotechnology Information [NCBI] (2024). PubChem Compound Summary for CID 6623, Bisphenol A. https://pubchem.ncbi.nlm.nih.gov/compound/Bisphenol-A
Park, H.-G., Kim, J.-Y. & Yeo, M.-K. (2016). Paper-based microfluide device for bisphenol A based chemical reaction and image analysis. BioChip Journal, 10, 25-33. https://doi.org/10.1007/s13206-016-0104-0
Pérez-Fernández V., Mainero Rocca L., Tomai P., Fanali S. & Gentili, A. (2017). Recent advancements and future trends in environmental analysis: Sample preparation, liquid chromatography and mass spectrometry. Analytica Chimica Acta, 983, 9-41. https://doi.org/10.1016/j.aca.2017.06.029
Rosenfeld, P. E. & Feng, L. G. H. (2011). Risks of Hazardous Wastes (pp. 215–222). Elsevier. https://doi.org/10.1016/b978-1-4377-7842-7.00016-7
Salgueiro-González, N., Muniategui-Lorenzo, S., López-Mahía, P. & Prada-Rodríguez D. (2017). Trends in analytical methodologies for the determination of alkylphenols and bisphenol A in water samples. Analytica Chimica Acta, 962, 1-14. https://doi.org/10.1016/j.aca.2017.01.035
Vasiliki, V., Pinto, P. C. A. G., Saraiva, M. L. M. F. S. & Lima, J. L. F. C. (2007). Sequential injection determination of meloxicam in pharmaceutical formulations with spectrophotometric detection. Canadian Journal of Analytical Sciences and Spectroscopy, 52, 351 – 358.
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